Friday, August 23, 2019

Journal of Biomedical Research and Review - BJSTR Journal

Abstract

#Oral candidiasis is an opportunistic infection of the oral cavity caused by the overgrowth of Candida species, usually of C. albicans. Candida species are present as #commensal organisms of the oral micro biota in about 20-60% of normal human population. The present article discusses about most common fungal infection of the oral cavity. The genus Candida belongs to yeasts. It is also the most common cause of opportunistic mycoses worldwide. It is a frequent colonizer of human skin and mucous membranes [1]. Candida is a member of normal flora of skin, mouth, vagina, and bowel. In addition to being a colonizer and a pathogen, it is found in the environment, particularly on leaves, flowers, water and soil. The genus Candida includes around 154 species. Among these, six are most frequently isolated in human infections. While Candidaalbicans is the most abundant and significant species, Candida tropicalis, #Candidaglabrata, Candida parapsilosis, Candida krusei, and Candida lusitaniae are also isolated as causative agents of Candida infections. Importantly, there has been a recent increase of infections due to non-albicans Candida spp., such as Candida glabrata and #Candida krusei. In the mouth, the primary site where C. albicans is located is the dorsum of tongue, while other places such as tooth surfaces covered with plaque are less commonly colonized.

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