Journals on Cancer Medicine - BJSTR Journal

Abstract

Chronic psychological stress is a main #etiological factor for autoimmune disease by releasing neuropeptides activates inflammatory mediators such as IL-iβ, TNF-α, IL-6, and COX-2. These inflammatory mediators induce NF-KB transcription factor involved in chronic inflammation, immune modulation, cellular changes, and tissue damage, augments an autoimmunity. Beta-endorphins is an abundant #endorphin, natural #neuropeptides synthesized and stored in the anterior pituitary gland through hypothalamus mediated by autonomic nervous system (ANS), in response to stressful conditions such as physical exercise, yoga, and meditation. Beta- endorphins involved in treatment of autoimmune diseases by reduction of stress and inflammation. This article highlights about the role of #beta-endorphins on auto-immune diseases.Endorphins are endogenous #morphine, #neuropeptides produced from pituitary gland in response to stress and pain. There are three types of endorphins p- endorphins, #enkephalins, and dynorphins binds to mu, kappa, and delta receptors located on nerves and immune cells.

For more articles on BJSTR Journal please click on https://biomedres.us/

For more Cancer Medicine Articles on BJSTR

https://biomedres.us/fulltexts/BJSTR.MS.ID.001667.php 

Beta- Endorphins- A Novel Holistic Therapeutic Approach to Autoimmune Diseases by Shrihari TG in BJSTR