Medical Humanities - BJSTR Journal

Abstract

#Betulin (Figure 1), lup-20(29)-en-3,28-diol, also known as betulinol, betuline and #betulinic alcohol, a principal component of birch bark, also found in Asparagus, barks and leaves from Punica, Ocimum, Zizyphus and other plants is a naturally occurring lupane-type #pentacyclic triterpene and exhibits a variety of activities [1-3]. Besides, betulin can be applied to food, cosmetics and pharmaceutical industries, with the activities of inhibiting the dissolution of the protein in hair fibers and improving the damaged hair reported in a patent application in United States. Antiallergenic Activity: There are so many studies that about antioxidant, anti-inflammatory, #hepatoprotective, antimutagenic and other activities of the extract of Lupane-type pentacyclic triterpenoids [4-6]. LP Kavolanko et al. studied the antiallergenic and anti-inflammatory activity of Birch bark dry extract (BBDE) containing betulin at least 70% betulin and betulin alone that compared with the reference drugs #Suprastin and #Claritin. The results indicated that the triterpenoid phyto complex BBDE possessed antiallergenic and anti-inflammatory activity that is stronger than betulin and indicated that the discovery of antiallergenic drugs based on BBDE is likely [7] (Figure 1).

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Research Progress in the Promissing Natural Product-Betulin by Shao Bin FU in BJSTR