Journals on Medical Microbiology - BJSTR Journal

Abstract

#Acinetobacter baumannii is a non-spore, non-motile, non-fer- mentable and aerobic gram-negative #coccobacilli which belongs to the #Moraxellacea family [1]. The most of this genus are opportunistic pathogens in both community and hospital acquired infections in #immunocompromised patients, especially in burn and ICU parts after Pseudomonas aeruginosa. These microorganisms have a significant role in various infections including bloodstream, pneumonia associated with ventilation, endocarditis, meningitis, skin, soft tissues, urinary tract and medical implant devices infection. The #Acinetobacter species are isolated from numerous sources, such as soil, water, animals and human tissues. Mentioned infections have been effectively treated with traditional antibiotics in the last three decades [2-4]. However, recently the resistance to the most classes of antibiotics such as broad-spectrum penicillin's, cephalosporins, #carbapenems, #fluoroquinolones, #chloramphenicol, #tetracyclines and most aminoglycosides has been reported. On the other hand, the emergence of multi-drug resistant strain (MDR) has been a global concern [5,6]. Among various antibiotic, #aminoglycosides are considered as one of the critical agents. Aminoglycosides process is divided in two different steps, first absorption in bacteria which is an important process for bioavailability and second stage is the binding to the ribosome and then inhibition of protein synthesis [7].

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Evaluation of Aminoglycoside Resistance Genes in Acinetobacter Baumannii Isolated from Different Parts of Babol Hospitals by Amirmorteza Ebrahimzadeh Namvar in BJSTR