Journals on Medical Microbiology - BJSTR Journal

Abstract

#Platelet concentrates are blood derivatives prepared from the patient's own blood in which the activated platelets become trapped within a fibrin matrix scaffold and release growth factors and #cytokines involved in the key processes of tissue regeneration; including cell proliferation and differentiation, extracellular matrix synthesis, #chemotaxis and #angiogenesis. These processes found to promote healing in both soft and hard tissues which led to successful therapeutic applications in medical and dental fields over the last two decades. Based on differences in #centrifugation speeds and times, adding chemicals, and the selection of #supernatants and precipitates; various preparations have been produced with different fibrin network structures, leukocyte content and growth factors and subsequent different physical and physiological properties and applications. The biology behind, the protocols for preparation and the science based evidence applications of different platelet concentrates in various fields of dentistry will be reviewed.

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Autologous #PlateletConcentratePreparations in Dentistry by Ola M Ezzatt in BJSTR