Biomedical Research Articles - BJSTR Journal

Abstract

Object: #Arachnoid cysts (AC) are benign, fluid-filled lesions of the #arachnoid membrane accounting for approximately 1% of intracranial lesions. We utilized 3D volumetric measurement techniques to evaluate AC volumetric changes with open #craniotomy or endoscopic approach for cyst fenestration in pediatric patients, focusing on correlation with patient age, clinical features, and surgical outcomes.

Methods: #Pediatric patients (≤18 years old) with AC who had undergone treatment with open craniotomy or #endoscopic approach for AC fenestration were identified from medical records. The volume of the intracranial AC were modeled before and after surgical intervention with Brain Lab software.

Results: Nineteen patients (3 females and 16 males) were included (mean age 6.5±5.5 years; range 0-18 years). The patients were distributed into three groups based on age: 0-3 years, 3.5-8 years, ≥9 years. Comparison of both pre- and post-operative volumes demonstrated no statistical difference between age groups, but evaluation of percent change between pre- and post-operative volumes revealed statistically significant greater decrease in volume reduction in both older age groups (3.5-8 years and ≥9 years) compared to the youngest age group (0-3 years). There was a trend toward increased improvement/resolution of presenting clinical symptoms with increasing age (p=0.01). #Subdural hematoma was found to be statistically lower in the 3-8 years group (p=0.03-0.05). Shunt placement was found to be statistically highest in the youngest age group (p=0.03).

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3D Modeling for Comparison of Surgically Treated Intracranial Arachnoid Cysts in Children by Julian Lin in BJSTR