Wednesday, January 1, 2020

Journals on Biomedical Science - BJSTR Journal

Abstract

#Multidrug resistant bacteria are marching and winning. The entire human race is at risk and new, effective antibiotics are needed for survival. Several notable routines to develop novel antibiotics are briefly compared here and possible new strategies are proposed. Key words include but not limited to nanotechnology, metal #nanoparticles, natural product, medicinal plants, folk medicine, #ethnopharmacology, computer-based screening, synergistic antibacterial activity, #genomics, peptides, inhibitor, and structure-based virtual screening.Threat from drug-resistant bacteria increases steadily and globally. As reported in 2016, over 700,000 people die, and millions suffer from drug-resistant pathogens each year. It is expected that 10 million people could be killed a year by 2050, based on the current rate of antibiotic approvals [1]. There are two main causes for the lack of effective, new #antibiotics. First, there has been no new antibiotics developed since 1980s. Most pharmaceutical companies dropped their program for antibiotic development after the peak of antibiotic discovery going back to 1940s [2].

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New Antibiotics: Where Are They? by Hua Deng in BJSTR
 
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