Abstract
Non-coding RNAs have retained a prominent role in regulating gene
expression. They are RNA species that are not transcribed but functional
participate in almost every aspect of cellular function. One of the
triggers of their discovery was the human #genome project. The number of
genes found in the human genome fluctuated during the analyses due to
the abundant non-coding RNAs that were difficult to be judged as a gene
or not. These non-coding RNAs are consisted of: #microRNAs (mi-RNAs) that
were found as RNAs transcribed form ultra-conserved regions; and other
evolutionary conserved ones such as circular RNAs (circ-RNAs) and long
non-coding RNAs (lnc-RNAs), as well as #PIWI-interacting RNAs, small
nucleolar RNAs, transcribed ultra conserved regions, and large
intergenic non-coding RNAs. The amount of these functional non-coding
RNAs have been increasing in a nearly exponential manner since their
discoveries and have been listed up to more than half of the transcribed
RNAs in the #human cell. This review will focus on non-coding RNAs
related with genes important for the function of the adrenal cortex.
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