Wednesday, January 8, 2020

Journals on Medical Microbiology - BJSTR Journal

Abstract

There is an increasing interest toward the understanding of the important fungus, #Aspergillus flavus, which has a high impact on our health and economy. Controlling such microbe could be achieved by evacuating its cells using simple tool. Recently, the #Sponge-Like protocol for bacterial ghosts' preparation was introduced. Then, this protocol concept was extended to include not only bacterial cells but also yeast cells as well as viruses. In this study, for the first time we applied this protocol to pathogenic fungi as #Aspergillus flavus turning it to unviable, dead and evacuated ghost cells. We introduce the idea of using the minimum growth concentration (MGC) and the minimum inhibition concentration (MIC) for controlling Aspergillus flavus and other type of fungi either in our food or those infecting us. Using mixture of compounds proves to have effect on certain microbes upon the use of their minimum effect, which could be a solution for treating many diseases without damaging the cells and tissues as well as our organs. A. flavus which is responsible for causing different superficial infections besides its ability to produce hazardous #aflatoxins was used as a model in this study.

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