Journals on Biomedical Science - BJSTR Journal

Abstract

The clinical discovery of #hyperbaric oxygen therapy dates back centuries ago. In last decades, and with the increasing knowledge of this treatment, the interest has extended to several areas of medicine. At present, there are some well-established indications based on scientific evidence. This review aims to summarize its mechanisms of action, current indications in the area of #Otorhinolaryngology, side effects and contraindications. #Hyperbaric Oxygen Therapy (HBOT) is defined as an intervention in which an individual breathes near 100% oxygen intermittently while inside a #hyperbaric chamber that is pressurized to greater than sea level pressure [1 atmosphere absolute (ATA), which converts to 101.325 kilopascals (kPa)]. For clinical purposes, the pressure must equal or exceed 1.4 ATA (141.86 kPa) while breathing near 100% oxygen. By breathing 100% oxygen at #high pressure, the oxygen dissolved in the plasma increases and consequently increases the oxygen that reaches the tissues. The application of compressed gas in medicine had its origins three centuries ago. Over the time there have been advances and setbacks in the history of this form of treatment due to lack of scientific evidence. It was only in the last four decades that good science existed to support some of its current applications [1-2].

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Hyperbaric Oxygen Therapy: Clinical Applications in Otorhinolaryngology by Joana Maria Soares Ferreira in BJSTR