Journal on Medical Research - BJSTR Journal

Abstract

Age-related #macular degeneration (AMD) is the leading cause of visual impairment and blindness after fifty years old in developed countries [1,2]. It is estimated AMD will affect 288 million of elderly in 2040 [3]. This pathology is defined by a uni- or bilateral progressive degeneration of #photoreceptors in macular area, peripheral vision is conserved. The early level of AMD is characterized by an accumulation of extracellular material (“drusen”) underneath the retinal pigment epithelium and/or irregularities of retinal pigment epithelium. At the advanced level of AMD, the disease gets complicated with a geographic atrophy in dry AMD, or a choroidal #neovascularization (growth of #pathologic blood vessel from the #choroide into the subretinal space) in the wet AMD. This one just affects 10-15% of AMD subjects but emerges and progresses quickly to blindness without #intravitreal injection (IVT) of anti-VEGF [4]. Thus, the majority of patients (dry AMD) has no curative treatment, loses visual acuity and his #autonomy step by step [5]. AMD gives functional disability (risk of falls, difficulty reading, driving restriction, etc). Some authors evaluated that 33% of subjects older than 65 years have experienced at least one fall per year [6,7].

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Postural Training in Age-Related Macular Degeneration Subjects: Issues and Impact by Hortense Chatard in BJSTR