Abstract
#Mushrooms are an excellent food option for diets, since they are
nourishing and not fattening, mainly due to their #nutritional characteristics. They have a high protein content, low lipid values,
besides the presence of vitamins (thiamine, riboflavin, niacin),
minerals (calcium, iron, phosphorus), beta-glucans and antioxidant
compounds. Several people are using it in Brazil as a blood glucose
level controller and Anvisa released the Agaricus blazei as a
#nutraceutical product. In the present project the objective was to
evaluate the healing of open cutaneous wounds in rats treated with
topical use of #Agaricus sylvaticus extract 10% in gel by
macroscopic analysis of the cicatricial process. For skin healing of
wound in rats, a total of 15 adults male Wistar rats (UNINOVE Vivarium)
were used, divided in three groups. Animals in group 1 were treated with
1mL of gel at 10% #Agaricus; group 2 with 1mL of distilled
aqueous gel and group 3 with fibrinase. Daily applications were
performed over the wound of total 4cm2 area in dorsal region
of each animal. The wound evaluation was made macroscopically in the
time stamps of 0, 7, and 14 days, and the wound evolution, and skin
healing retraction measures evaluated by digital planimetry.
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Effect of Agaricus Sylvaticus (Schaeffer) Extract in Rats Skin Wound Healing by Erna Elisabeth Bach in BJSTR
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