Abstract
Background: Higher cardiac as also general mortality in
eastern regions of Finland than in the west, has been decades without
satisfactory explanation. High number of annual rainy days (RD) and
lower #serum vitamin D values has been associated with East Finland
relative to South Finland. Enrichment of dairy products was begun in
2002. In this study has been assessed regional CHD mortality (a sign of
CHD morbidity) from 1964-84 [CHD. (64-84)] and CHD morbidity from
2012-14 [CHD. (12-14)], their association strength and stability with
latitude (Lat), longitude (Long), altitude (Alt), RD and groundwater
silicon (Si.gw). Areal parts of #Uusimaa were combined to one unit, as
respectively by #Varsinais-Suomi. Number of area units was 18.
Results (R square %'s): [CHD. (64-84)]/ [CHD. (12-14)]
associations: Long: 86/52.7%; RD: 61.3/44.2 %; Si.gw: 41.8/38.2 %; Alt:
33.5/32.3 %; Lat 15.8/42.6 %. Alt explained best Si.gw (50.2 %). Long
explained best RD. Changes in CHD associations were highest with Lat and
Long, smallest with Alt and Si.gw. (Significance: if R square % >
21.8, p < 0.05; if > 34.0, p < 0.01).
Conclusion: CHD morbidity showed high inter-regional stability
between several decades and was associated significantly with the number
of RD in both periods and suggested on CHD association with serum
vitamin D content. Anyhow decrease in CHD E/W ratio until period 2012-14
was mostly occurred before #D-vitamin fortification.
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Rainy Days, Geographic Coordinates, Vitamin D, Silicon, Selenium and CHD in Finland in 1962-2014 by Toysa T in BJSTR
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